Discussions in Infection Control

An independent site by Lawrence F Muscarella PhD -- a national authority on the causes and prevention of healthcare-associated infections and related errors.

Category: Toxic Anterior Segment Syndrome

Cleaning Agents Detergents Enzymatic Flash Sterilization Immediate-Use Steam Sterilization Steam Sterilization Toxic Anterior Segment Syndrome

Are Enzymatic Detergents the Primary Cause of The Inflammatory Eye Reaction Called TASS? A recently published article investigates risk factors for TASS.

March 31, 2018 Lawrence F Muscarella PhD

March 31, 2018 (11:21 am) — Improper cleaning and sterilization of reusable ophthalmic instruments used to perform cataract and other intraocular surgeries is one of several risk factors for TASS,…

Aseptic Technique Biological Indicators Carbapenem-Resistant Enterobacteriaceae (CRE) Critical Device Classifications Disease Transmission Endoscope Reprocessing Flexible "ENT" Laryngoscopes Food and Drug Administration High-Level Disinfection Hydraulic Fluid Infection Prevention Instrument Drying Intermediate-Level Disinfection Liquid Chemical Sterilization Low-Level Disinfection Noncritical Ophthalmic Instruments Patty Murray (U.S. Senator) Rigid Laryngoscopes Semicritical Devices Skin Electrodes (Reusable) Sterility Sterilization Toxic Anterior Segment Syndrome

Response to the FDA’s Draft Guidance Document on the Reprocessing of Reusable Medical Devices

February 7, 2015 Lawrence F Muscarella PhD

February 5, 2015 — This article presents Dr. Muscarella’s response submitted in August 2011 to the federal Food and Drug Administration (FDA), in reply to the Agency’s request earlier that…

Centers for Disease Control and Prevention Centers for Medicare and Medicaid Services (CMS) Flash Sterilization Healthcare Quality, Safety Healthcare-Acquired Infections Immediate-Use Steam Sterilization Infection Prevention Sterilization Toxic Anterior Segment Syndrome

Flash or Immediate Use Steam Sterilization: A Position Statement

August 22, 2014 Lawrence F Muscarella PhD

This article presents the position of Lawrence F Muscarella, PhD, on the use of “immediate-use steam sterilization” (IUSS), historically known as “flash sterilization,” to process surgical instruments in or near…

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August 2, 2023 Lawrence F Muscarella PhD
Adverse Event Reports Candida auris Carbapenem-Resistant Enterobacteriaceae (CRE) Duodenoscopes Endoscope Reprocessing Escherichia coli Gastroscopes MAUDE Medical Device Reports (MDRs) Risk Assessment Single-Use Disposable Devices

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January 6, 2023 Lawrence F Muscarella PhD